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Long before fish oil was marketed as “heart healthy,” early animal research had already raised red flags. Studies from the mid-20th century onward showed that diets high in fish oil accelerated lipid peroxidation, increased lipofuscin (age pigment) accumulation, caused liver damage, suppressed immune function, and led to gonadal degeneration in animals. These effects were linked to the extreme instability of omega-3 polyunsaturated fats, which oxidize easily and disrupt mitochondrial respiration
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Short videos

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