Mammalian target of rapamycin (mTOR) is a kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. [5][6] It also promotes the …

Oct 2, 2023 · The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular metabolism, catabolism, immune responses, autophagy, survival, proliferation, and migration, to …

Notably, mTOR plays a pivotal role in cardiovascular health and disease, particularly in the onset and progression of cardiac conditions. In this review, we discuss mTOR’s structure and function as well …

Aug 5, 2025 · It acts as a central hub, sensing the cell’s internal and external environment to regulate growth, metabolism, and survival. By integrating various signals, mTOR helps maintain cellular …

Jul 8, 2025 · The mammalian/mechanistic target of rapamycin (mTOR) is an evolutionarily conserved multi-node signaling pathway that integrates critical environmental cues to control cellular growth.

Aug 19, 2025 · The mammalian target of rapamycin (mTOR) is a master regulator of cell growth, nutrient sensing, and metabolism. It acts like a central switchboard, integrating signals from food, hormones, …

Jul 8, 2025 · Decades worth of studies have intricately dissected the mTOR pathway to identify regulatory signals that are essential for regulating immune cell activation, differentiation, and …

Nov 3, 2025 · The mechanistic target of rapamycin (mTOR) is a serine/threonine kinase involved in platelet signaling and thrombus stabilization in vitro. Platelet mTOR is upregulated in aging and …

Jan 5, 2024 · Learn about the mTOR signaling pathway, its role in cell growth and metabolism, and its therapeutic targeting. Explore the pathophysiological implications and regulation of mTOR.

TOR is found in 2 structurally and functionally distinct multiprotein complexes, TORC1 and TORC2. The 2 TOR complexes, like TOR itself, are highly conserved. Mammalian TORC1 (mTORC1) is …