The EMBO Journal2d
The winter holidays are glorious—except when they’re not
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
The EMBO Journal8d
Rett syndrome: interferon-γ to the rescue?
In conclusion, this intriguing report builds on the work of many other groups by further unraveling MECP2 function in the ...
The EMBO Journal11d
TRPC5: a new entry to the chromaffin cell’s palette of ion channels that control adrenal response to hypoglycemia
Hypoglycemia is an extremely common side effect of insulin therapy experienced mainly by patients with type 1 diabetes ...
The EMBO Journal11d
Genetic linkage disequilibrium of deleterious mutations in threatened mammals
LDcor and its standardized form, nLDcor, which analyze the global linkage disequilibrium of deleterious mutations across ...
The EMBO Journal13d
Brain mitophagy in space and time
A new resource by Rappe et al (2024) now provides a spatiotemporal landscape of mitophagy changes during mouse brain aging at ...
The EMBO Journal7d
Making contact away from home: a bacterial secreted effector mediates inter-organelle communication
Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...
The EMBO Journal2d
Circadian rhythms of macrophages are altered by the acidic tumor microenvironment
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Tumor-associated macrophages (TAMs) are prime ...
The EMBO Journal3d
PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Poly(ADP-ribose) polymerase 1 (PARP1) is one ...
The EMBO Journal3d
Glutamine sensing licenses cholesterol synthesis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mevalonate pathway produces essential ...
The EMBO Journal9d
Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Lipid droplets (LDs) serve as crucial hubs for ...
The EMBO Journal20d
Cyclophilin D plays a critical role in the survival of senescent cells
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Senescent cells present an excessive flux of ...
The EMBO Journal16d
Deep quantification of substrate turnover defines protease subsite cooperativity
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Substrate specificity determines protease ...