Steps Forward: Immunoassays for cryptic HDGFL2 flag TDP-43 proteinopathy in diverse disorders. Companies have moved a PET ligand into Phase 1 trials.

A documentary of country legend Glen Campbell's life and “Goodbye Tour” following his diagnosis of Alzheimer's ...

Other Phenotypes Premature death, attributed to hindbrain tauopathy, generally occurs between eight and 12 months (Dutschmann et al., 2010). Premature death is preceded by weight loss, hyperkyphosis, ...

Findings The presence of three copies of chromosome 21, which harbors the amyloid precursor protein (APP) gene, is the most common genetic cause of Alzheimer’s disease. Carriers of this alteration ...

T cells have been found in the brain meninges as well (May 2021 news; Feb 2025 news), but flow cytometry and single-cell RNA sequencing confirmed that these SFO CD4+ T cells are distinct. They ...

To narrow down the number of scents needed for such a test, Li first ranked each of the 16 SST-ID and 40 UPSIT scents for their ability to distinguish PD/DLB from controls in three cohorts—the De Novo ...

Since February, the termination of some 2,482 grants worth $8.6 billion has shaken the scientific community, including AD researchers. Thanks to government databases and intrepid scientists tracking ...

To report consequences on AD research, Alzforum has spoken with scientists across the board, including some whose research has been subject to funding cuts, as well as some who have so far remained ...

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) ...

Awards will be for up to $475,000 in Direct Costs per year, plus applicable Facilities and Administrative (F&A) costs ...

Award NIH intends to commit approximately $8 million in FY 2026 to fund approximately 8 awards. Awards will be for $700,000 in Direct Costs per year, plus applicable Facilities and Administrative ...

Interestingly, across the board, women had more taurine in their plasma than did men, and their levels ticked up more erratically throughout life (image below). Indeed, the Emory study found no change ...