The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the ...

Cardiovascular disease has been the leading cause of mortality and morbidity worldwide in the past 3 decades. Multiple cell lineages undergo dynamic alternations in gene expression, cell state ...

Sudden cardiac death (SCD) in young athletes, although uncommon, is a tragic event, shocking the family, the sports medical team, and the local community. SCD in young athletes is widely publicized by ...

In this issue, Porcari and Gillmore 3 evaluated RV uptake on 99mTc-PYP/DPD/HMDP SPECT images of patients diagnosed with ATTR-CM and determined its prognostic significance. This retrospective analysis ...

One major difference between re-entrant and non– re-entrant ventricular tachycardia (VT) is that the electrophysiological substrate for re-entry is acquired during postnatal development and is due to ...

A foundational concept in cardiac electrophysiology is that understanding the cellular mechanism of an arrhythmia provides essential insight for developing targeted therapeutic options. However, ...

Because of structural and cellular differences (ie, degrees of matrix abundance and cross-linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison to capillaries, ...

This interdisciplinary review explores the intricate nexus between HIV infection, nutrition, adrenal gland function, and cardiovascular health, highlighting a critical aspect of HIV management often ...

We conditionally ablated Fstl1 from the endocardial lineage using a transgenic Tie2-Cre mouse model. These mice showed a sustained Bmp and Tgfβ signaling after birth. This resulted in ongoing ...

I. The Problem: Childhood Obesity—A Burgeoning Epidemic Over the past 30 years, the prevalence of obesity has nearly tripled for children 2 to 5 years of age and youth 12 to 19 years of age, and it ...

Left heart disease (LHD) affects ≈10% of the population over the age of 20 years in the United States with coronary disease as the leading cause of death. 1 Heart failure (HF)—the end result of ...

Rationale:Lymphatic vessels function to drain interstitial fluid from a variety of tissues. Although shear stress generated by fluid flow is known to trigger lymphatic expansion and remodeling, the ...