Mario & Luigi: Brothership doesn't contain many boss fights, but every once in a while the game will throw a tough obstacle in the player's path. One of these is Gobblick, the guardian boss of the first Great Lighthouse Island. This island and boss unlock after the player completes all prior islands in the Lushgreen Sea.

Brothership makes one small change to Luigi's combat controls, and many fans of the RPG series are upset about it.