Oral submucous fibrosis (OSF) is a serious disease that impairs mouth functionality, often leading to restricted opening and ...

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular ...

We first address the etiopathophysiology of OA and the mechanisms responsible for breakdown of the cartilage extracellular matrix. We then discuss the potential of MSCs for articular cartilage ...

In the case of biofilms, the nature of the extracellular matrix makes SERS methods particularly challenging since it is chemically complex, contains multiple constituents known to interact strongly ...

Medical Engineering & Engineering Medicine Innovation Center, Hangzhou International Innovation Institute, Beihang University, Hangzhou 311115, China Key Laboratory of Biomechanics and Mechanobiology ...

ECs with increased CircOGDH expression were analyzed for changes in COL4A4 (collagen type IV alpha 4) levels, and in vitro coculture experiments were conducted to examine small extracellular ...

Invitrogen Cat# MA137493 Detects cartilage matrix in immunofluorescence (1:200) Antibody Anti-Collagen I (Rabbit monoclonal) Abcam Cat# ab138492 Used for extracellular matrix immunostaining (1:200) ...

It is known that MMP13 is significantly overexpressed in the joints and articular cartilage in patients with OA, and is a major proteinase involved in the degradation of type II collagen, a key ...

Step 4: p-cMGP is secreted into the extracellular matrix or the circulation to inhibit soft tissue calcification, VSMC (vascular smooth muscle cell) trans-differentiation into OPC (osteochondrogenic ...

A wide range of transcription factors regulated by soluble extracellular signaling ... generation of a provisional matrix. Similarly, there is scant evidence that other non-articular derived MSCs are ...