A new study reveals that the protein Lcn2, secreted by lung macrophages, plays a central role in exacerbating severe pneumonia caused by Severe Acute ...

(A) SA-β-Gal staining of ACE2/A549 cells in different groups, bar = 100μm; (B) Protein levels of p16, p21, and (C) quantitative analysis in different treatments; (D) Protein levels of β-catenin and (E ...

New Delhi: Changes in the spike protein enhanced the ability of the coronavirus to infect the brain, which could underlie the brain-related symptoms of the disease, including brain fog of long ...

Figure 1. Lung images following intranasal administered SARS-CoV-2 Spike protein. (A) Confocal micrograph of a lung section 18 hr post SARS-CoV-2 Spike protein (Trimer) instillation. Alveolar ...

Methods: MCA/FeCl 3 thromboembolic model was induced in humanized ACE2 knock-in mice. hACE2 mice were treated with Losartan, an angiotensin receptor blocker, after one day of SARS-CoV-2 spike protein ...

Vaccine-makers should stop including the spike protein of the original SARS-CoV-2 coronavirus in covid-19 booster jabs to make them more effective against current variants, a study of antibody ...

In humans, lingering spike protein was seen in 10 of 34 skull samples of people who had recovered from SARS-CoV-2 infection and died of non-COVID-related causes in 2021 and 2022.

New research reveals that mutations in the stem of the SARS-CoV-2 spike protein led to the virus becoming progressively tighter over time, which may have improved the virus's ability to transmit ...

This fundamental and timely study provides insights into the structural dynamics of several relevant mutant forms of SARS-CoV-2 spike protein, including the most recent omicron variant. The ...

University of Sydney scientists have discovered a protein in the lung that naturally blocks SARS-CoV-2 infection opening a pathway for new COVID-19 drug development.

With myocarditis, the spike protein most likely arises downstream from the vaccine itself, not leftover virus, she explained. Typically, though, these particles don’t stick around but get cleared as ...

We demonstrate that these nanobodies competitively inhibit binding between the SARS-CoV-2 spike protein receptor binding domain and its human receptor protein, angiotensin converting enzyme 2. There ...