An SCD patient in Bahrain received the gene-editing therapy Casgevy, marking the first time the treatment has been given outside the U.S.

New gene therapies could transform sickle cell treatment forever. A future without pain crises or hospitalizations may finally be within reach.

Objective This study aims to evaluate the markers of tubular phosphate handling in adults with sickle cell anemia (SCA) and the influence of hydroxyurea (HU), the degree of anemia and Hb F ...

A cutting-edge gene therapy has been approved for NHS use for some patients with severe sickle cell disease. Casgevy, also known as exa-cel, was the first treatment to be licensed using gene ...

Sickle-cell anaemia is the name of a specific form of sickle-cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell anaemia is also referred to as "HbSS", "SS ...

Sickle cell anaemia, a hereditary condition that primarily affects African and Mediterranean populations, continues to pose significant health challenges. In Uganda, where the disease is prevalent ...

This article is part of a Health Affairs Forefront series on “The Future of Sickle Cell Disease Research and Care” with support from The American Society of Hematology. The articles in the ...

Study: Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease. Image Credit: Shutterstock AI / Shutterstock.com A recent study published in Cell reveals that the ...

and heart disease, in affluent countries such as Ireland. A paper published today in the scientific journal Cell shows that a newly developed diet that mimics eating habits in non-industrialissed ...