Sure enough, SGLT2 inhibition with canagliflozin significantly reduced the previously elevated number of PD-L1-positive senescent cells in HFD-fed mice. Conversely, suppression of immune cells ...

Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, ...

Researchers have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer ...

The virus takes control of three key host proteins that suppress the activity of the complement system. Researchers at the ...

The discovery offers insight into why shift workers experience metabolic disruption, which could lead to new therapies for managing obesity and preventing muscle wasting. Recent research shows that ...

Renal glucose reabsorption involves two transporter families: the SGLTs secondary active Na + /D-glucose co-transporters located at the brush border of tubular cells (SGLT2 and SGLT1) and the ...

The new technique could kill a wide range of cancer cells, including breast and prostate A newly-discovered part of our immune system could be harnessed to treat all cancers, say scientists.

Researchers Make Glioblastoma Cells Visible to Attacking Immune Cells Nov. 7, 2024 — Researchers have identified a possible way to make glioblastoma cells vulnerable to different types of ...

Prof. Fabry emphasizes, "Our discovery that immune cells can create high contraction forces for a brief period of time is only one example of how this new method will lead to fundamental discoveries.

Of note, a similar proportion of patients in the empagliflozin and placebo groups (43% and 40%, respectively) were using an SGLT2 inhibitor during the post-trial period, they wrote in the New ...

When thinking about the immune system, most people think about B and T cells and how they can be trained to recognize ...

"It's his rebirth." It will be a month before tests reveal whether Cedric's new cells have taken root, but in a way he's lucky. All he needs is a new blood supply and immune system, which are ...