New research has identified the gene Egr-1 as a critical regulator of immune balance, offering hope for autoimmune disease therapies.

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

Glial cells support neurological structures, function, cognition, behaviours, physical skills, and motor coordination.

An international research team has deciphered a mechanism of the evolutionary arms race in human cells. The findings provide ...

Microglia replacement therapy helps treat people with a rare genetic condition called ALSP, suggesting the approach could ...

Objective To elucidate crucial immune cell subsets and associated immunological pathways by stratifying patients with immune-mediated diseases (IMDs) using immunophenotyping and transcriptomic ...

DPP-4i provides modest endogenous GLP-1 elevation (2-3-fold) and, due to DPP-4's broad substrate profile including inflammatory chemokines, neuropeptides, and growth factors, simultaneously affect ...

The sodium glucose co-transporter 2 (SGLT2) receptor inhibitors are a new class of glucose-lowering agents. Objective To assess the clinical effectiveness and safety of the SGLT2 receptor inhibitors ...

An engineered protein turns off the kind of immune cells most likely to damage tissue as part of type-1 diabetes, hepatitis, ...

Discover how high fructose levels can trigger immune overreaction, leading to inflammation and potential food sensitivities.

Cornell researchers have discovered that immune tolerance to gut microbes depends on a bacterial-sensing protein called STING, previously known mainly for triggering inflammation, according to the ...