IgA nephropathy (IgAN) is an autoimmune kidney disease driven by immune cells that express a protein called CD38 on their surface. Sodium-glucose co-transporter 2 (SGLT2) inhibitors reduce the ...

NEW RESEARCH presented at EASD 2024 revealed that maternal Type 1 diabetes (T1D) provides long-term relative protection ...

It's a podocyte driven disease and the only way you can reduce proteinuria is to make that cell healthier and Sparsentan ... target the kidney as well as the immune system really resonates with ...

Elevated concentrations of AcAc, especially at high glucose levels, aggravate endothelial cell injury through oxidative stress ... in microRNA levels during caloric restriction can maintain immune ...

Researchers have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer ...

The discovery offers insight into why shift workers experience metabolic disruption, which could lead to new therapies for ...

Researchers combined advanced imaging techniques with a computational method to probe how immune cells interact with each other, revealing that the interactions between immune cells in the vicinity of ...

Prof. Fabry emphasizes, "Our discovery that immune cells can create high contraction forces for a brief period of time is only one example of how this new method will lead to fundamental discoveries.