The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2. Although vaccines ...

Findings show potential for new lipid-based delivery formulations as a platform technology for immunizationPhiladelphia, PA, ...

Concurrent analysis of whole-genome DNA methylation and single-cell RNA sequencing data from COVID-19 patients and controls ...

Small-molecule inhibitors targeting viral proteins could serve as an effective alternative for controlling the spread of COVID-19 at both individual and community levels. In this vein, a recent study ...

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating ...

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells ...

Successful high-affinity B cells can proliferate under special conditions that reduce the risk of mutation. Capturing this ...

Bispecific antibodies targeting multiple SARS-CoV-2 sites offer enhanced neutralization against emerging variants, advancing ...

We assessed the ESMFold language model ... studies of protein–peptide complexes using X-ray crystallography and NMR spectroscopy are insightful, they are also expensive, time-consuming, and face ...

Xinjiang Engineering Research Center of Big Data and Intelligent Software, School of Software, Xinjiang University, Urumqi 830091, China Key Laboratory of Software Engineering, Xinjiang University, ...

encoded for the SARS-COV-2 antigen, to the skin of animals in a preclinical model, resulting in robust antibody and cell-based immune responses. SARS-CoV-2 continues to be a health burden globally ...