Sleep's role to down-scale glutamate, excitatory, frontal cortical synapses is extended to include an up-scaling of metaplastic LTP potential, in recovery from prolonged waking induced saturation of ...

Q4 2024 Earnings Call Transcript February 11, 2025 Arvinas, Inc. beats earnings expectations. Reported EPS is $-0.63, ...

The primary endpoint is objective response rate, with progression-free survival a key secondary endpoint. The study includes a pre-registration step for arm determination by the molecular tumor board.

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Biocrusts, covering much of Earth’s drylands, are crucial, yet endangered ecosystems. This study sequences the chromosome-level genomes of two biocrust algae, Bracteacoccus bullatus and B. minor ...

Presa, Bailey et al. assess the feasibility and efficacy of intrathecal administration of AAV9-SUMF1 gene therapy in the Sumf1-KO mouse model of Multiple Sulfatase Deficiency. They show that it ...

Arvinas Inc. (ARVN) reported its earnings for the fourth quarter of 2024, revealing a smaller-than-expected loss per share ...

Feb. 6, 2025 — Despite new medication, cystic fibrosis often leads to permanent lung damage. Researchers have discovered that the disease causes changes in the immune system early in life ...