If you think of any Hollywood heartthrob, they'll no doubt have appeared in People 's Sexiest Man of the Year issue.

In this third film, after breaking up with Mark Darcy (Colin Firth), Bridget (Renée Zellweger) has a one-night fling with Jack Qwant (Patrick Dempsey). She falls pregnant, but who’s the father?

Grey’s Anatomy star Patrick Dempsey has opened up about his changing appearance in a very candid confession. Now, any fans of ...

We are on the verge of a new Sexiest Man Alive being named by People Magazine. Such a title certainly gives the chosen star ...

Patrick Dempsey has confirmed that he is now in official talks to star in Scream 7 and reprise the role of Mark Kincaid. Now, Patrick has responded to the rumours and revealed where he's at in ...

Patrick Dempsey sparked excitement among Scream fans during his Thursday appearance on Today. While discussing his charitable work at The Dempsey Center, providing free comprehensive cancer care ...

Patrick Dempsey will play his big boss, Aaron Spencer, and the ex Grey's Anatomy actor also revealed more details about his character's relationship with the serial killer with a code. Tonally ...

Patrick Dempsey says his eyes were opened when his mom was diagnosed with cancer. In an exclusive conversation with PEOPLE, the actor, 58, speaks candidly about his mom Amanda Dempsey's cancer ...

EXCLUSIVE: Minnie Driver (Good Will Hunting) and Patrick Dempsey (Grey’s Anatomy) are in talks to star in Emma-Kate Croghan’s dramedy The Household Guide to Dying, based on the book by Debra ...

Up next, Dempsey will appear in the Dexter prequel, Original Sin. He’ll portray Aaron Spencer, the captain of the Miami Metro Homicide who has a decades-long relationship with Christian Slater ...

Patrick Dempsey, starring in an upcoming thriller series, expresses excitement about the collaborative environment on set. Praising creator Clyde Phillips, he highlights the importance of work ...