Age-related changes in blood stem cells are linked to decreased platelet factor 4, marking a critical finding for treating ...
The increasing knowledge of barrier tissue-resident memory macrophages and trained innate immunity (TII) will help develop both nontarget-specific and target-specific TII-based vaccine strategies.
Hematopoietic reprogramming reflects the selective and evolutionarily conserved engagement of transcription factor networks that encode innate immune memory in long-lived stem cells.
The discontinued CAR T therapy bbT369 came to Regeneron when the pharma bought all of 2seventy bio’s pipeline assets for $5 ...
First and only therapy FDA approved in both R/R acute myeloid leukemia (AML) with an NPM1 mutation and R/R acute leukemia with a KMT2A ...
The FDA has approved revumenib (Revuforj; Syndax Pharmaceuticals) for patients aged 1 year and older with relapsed or ...
Sebastién Maury, MD, PhD, discusses the protective capacity of RSV vaccinations for adult patients who have undergone HSCT.
The team went on to build a new engager that activates all three NK cell types to target treatment-resistant forms of non-Hodgkin’s lymphoma 3 ... described how they used ATAC-seq to study acute ...
A cancer diagnosis can be overwhelming, but today there is more reason for hope than ever before – survival and recovery are increasingly possible. At the heart of this progress is technology that not ...
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the ...
Human interleukin-26 (IL-26) is linked to intestinal inflammation and is bactericidal in vitro. This study uses zebrafish as ...