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The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...
Longitudinally measuring and forecasting changes in DNA methylation can reveal patterns of ageing and disease progression, but biosamples may not always be available. We introduce a probabilistic ...
This pathway, or others like it, could explain why some inheritable traits between generations can’t be explained exclusively via DNA and RNA. "There are a lot of traits and disorders that we ...
“We know the final protein sequence has to stay the same, but the genetic code is redundant meaning the RNA design can be flexible. A major question is if we change this codon or that codon, does that ...
“When I did the review I met with RNA officials and it was glaringly obvious it needed a facelift. “It just wasn’t going to work (as the main stadium) within the budget framework and ...
The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting hepatic synthesis of lipoprotein(a), are unknown. We randomly assigned participants in a 1:2:2:2:2 ...
School of Public Health, Food Safety and Health Research Center, Guangdong Provincial Key Laboratory of Tropical Disease Research, Southern Medical University, Guangzhou 510515, China ...
Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the ...
One of the most abundant and significant modifications in RNA is m6A, which influences RNA processing, stability, and translation into proteins. However, its role in cancer-particularly prostate ...