Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ.

Our blood consists of many cell types that develop through different stages from a precursor type -- the blood stem cell. An international research team has now investigated the developmental pathways ...

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...

A consortium of Austrian research groups from the University of Vienna, MedUni Vienna and Technikum Wien, together with ...

Our blood consists of many cell types that develop through different stages from a precursor type—the blood stem cell. An ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

With the theoretical part extended, this paper would be of interest to cell biologists and biophysicists working on asymmetric partitioning during cell division. Asymmetric partition of fate ...

Bone morphogenetic proteins (BMPs) directly affect the osteogenic differentiation of stem cells and are integral to bone ...

Cancer Discovery publishes high-impact articles featuring major advances in research and clinical trials. Topics span the spectrum of cancer research and medicine from the laboratory to the clinic to ...

The cornea is the clear, outermost layer of the eye. Its outer border, the limbus, contains a large volume of healthy stem ...

Cancer stem cells (GSCs), a small fraction of the tumor cells ... The stemness of GSCs was verified by multidirectional differentiation immunofluorescence staining (Figure 2A). Normal peripheral blood ...

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