Histone deacetylation and other modifications, particularly the methylation of lysine 9 within histone H3 (H3-K9) residues located in the histone tails, cause chromatin condensation and block ...

Thus, histone modifications generally represent a more complex and diverse mechanism to affect gene transcription than DNA methylation. In fact, one effect of DNA methylation can be to recruit ...

The most popular of these treatments aim to alter either DNA methylation or histone acetylation. Inhibitors of DNA methylation can reactivate genes that have been silenced. Two examples of these ...

"The changes that happen with the fat exposure, the changes in metabolism and the changes in histone methylation and gene expression are the types of changes that can be associated with hormone ...

Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for innovative therapeutic strategies.

To compact the DNA, plants use various epigenetic marks, including DNA methylation and modifications of the histone proteins ...

Discover how histone modifications unlock secrets of human aging, rivaling the precision of DNA methylation in decoding biological age. In a recent study published in the journal Science Advances ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

Biological processes are also under intensive regulation at the epigenomic level. We aim to understand the functions of DNA methylation and histone modifications in these processes and to provide new ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact ...