Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for ...

Longitudinally measuring and forecasting changes in DNA methylation can reveal patterns of ageing and disease progression, but biosamples may not always be available. We introduce a probabilistic ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin 300072, China ...

"The changes that happen with the fat exposure, the changes in metabolism and the changes in histone methylation and gene expression are the types of changes that can be associated with hormone ...

Department of Pharmacy, Universidade Federal dos Vales do Jequitinhonha e Mucuri-UFVJM, Campus JK, Rodovia MGT 367 - Km 583, n° 5.000, Alto da Jacuba, CEP 39100-000 Diamantina, MG, Brazil ...

“Today, when we don’t know what causes a disease, we say it’s likely epigenetic. In a sense, I think this epigenetic viewpoint is right, but we need much more evidence to get a defined picture.” Cedar ...

This review focuses on one of the main epigenetic mechanisms, namely, the methylation of the histone H3 at various sites and its involvement in male urogenital cancers. This histone modification ...