The pre-analytical workflow is one of the primary considerations in the successful use of liquid biopsies for cancer ...

Researchers developed a cost-effective assay to be used with chemicals and potential carcinogens associated with reversible ...

This includes comparative (tumour cell versus normal cell) investigation of nuclear organization, DNA methylation, histone modification and the consequences of genetic mutations in genes encoding ...

have demanded more advanced tools. Enter DNA methylation- a subtle but incredibly powerful layer of genetic regulation that is now transforming the forensic landscape. DNA methylation is a ...

The study by Li et al. provides fundamental findings supported by convincing evidence that they defined cellular reprogramming of androgen receptor in neuroendocrine prostate cancer (NEPC). The ...

Specifically, PRC2 adds a well-known repressive tag called H3K27me3 to histone proteins; while PRC1 adds related tags, H2Aub or H2A.Zub, to the histone H2A or a variant histone called H2A.Z ...

The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...

Two closely related Arabidopsis RPD3-type histone deacetylases HDA19 and HDA6, exhibit functional divergence, yet the molecular mechanisms underlying this divergence remain largely unclear. This study ...

Mar. 26, 2025 — Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the ...