Researchers from Mass General Brigham and the Broad Institute of MIT and Harvard have identified genetic modifications that can improve the efficacy of chimeric antigen receptor (CAR)-T cell treatment ...

Dr. Ambroise Wonkam, director of the McKusick-Nathans Institute and Department of Genetic Medicine at the Johns Hopkins University School of Medicine, is dedicated to studying genetic and genomic ...

When Dr. Ambroise Wonkam walked into a panel on medical genetics out of curiosity, he had no idea it would shape the course of his career. Born in Cameroon, Wonkam has dedicated his career to studying ...

Beta-thalassemia is a genetic disorder that significantly burdens healthcare systems globally. This inherited blood disorder, categorized into beta-thalassemia and alpha-thalassemia, results in ...

The breakthrough was achieved in an Investigator-Initiated Trial (IIT) conducted in collaboration with the First Affiliated Hospital of Guangxi Medical University. The patient demonstrated a ...

For years, researchers have been trying to figure out how to treat inherited blood disorders like sickle cell disease without causing new health problems in the process. Now, a team of scientists from ...

CAMBRIDGE, Mass., Aug. 14, 2025 (GLOBE NEWSWIRE) -- Beam Therapeutics Inc. (Nasdaq: BEAM), a biotechnology company developing precision genetic medicines through base editing, today announced that the ...

― Robust and clinically meaningful absolute mean fetal hemoglobin (HbF) induction of 8.6% from baseline at 12 weeks of treatment; 7 of 16 patients achieved absolute HbF levels greater than 20% ― ― ...

Dias–Logan syndrome (DLS) is a rare condition caused by heterozygous germline BCL11A pathogenic variants associated with global developmental delay, distinctive facial features, and asymptomatic ...

Researchers from the University of Maryland’s Department of Nutrition and Food Science are shedding new light on how a dangerous foodborne pathogen—Cronobacter sakazakii—may have adapted to thrive in ...