The switch from HbF (α2γ2) to HbA (α2β2) is critical in the pathophysiological processes underlying the major hemoglobin disorders, which are caused by mutations of the β-globin gene .

The first healthy volunteer has been dosed in a Phase 1 study of Cellarity's novel globin-switching therapy CLY-124 for ...

Japan: Researchers have found in a new study that Roxadustat therapy in non-dialyzed chronic kidney disease (CKD) patients may lead to hemoglobin (Hb) overshoot, particularly when switching ...

The $2,063,848 National Institute of Diabetes and Digestive and Kidney Diseases grant will support research on "hemoglobin switching and erythroid differentiation," the release said, noting that the ...

Hemoglobin SC disease, or Hg SC disease, occurs when the gene that tells our body how to make hemoglobin mutates. These mutations change the shape of red blood cells. It's a genetic condition you ...

Hemoglobin is a vital component of your blood. Learn why doctors test your hemoglobin levels during routine blood work and what abnormal results may mean.