A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — ...

Metabolic inflammation is a chronic, low-grade systemic condition that crucially impacts several major diseases, including ...

Researchers discovered that targeting S. pyogenes metabolism with a pyruvate dehydrogenase inhibitor reduces tissue damage ...

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, ...

According to the latest information released by the Fungicide Resistance Action Committee (FRAC), over 30 fungicide selective targets have been identified and acknowledged in the field of fungicide ...

However, several Trp metabolism end-products are essential to intestinal homeostasis. Here, we investigated the role of metabolites from the kynurenine pathway. Design Targeted quantitative ...

While single reactions and metabolic pathways have been studied in detail, it has been painstaking to determine which are active or 'carry flux' in a given cell, at a given moment. The first paper ...

To bridge this gap, 3Z Pharmaceuticals employed an advanced systems biology approach, integrating cross-species analysis using the zebrafish adgrl3.1 ADHD model with targeted metabolomic profiling to ...

prausnitzii making people feel better? One answer, we think, might be that these bacteria use a metabolic pathway known as the S-adenosyl-L-methionine cycle I pathway to influence levels of two ...

Department of Orthopedic Trauma and Microsurgery of Zhongnan Hospital & Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, PR ...