Learn what distinguishes alpha- from beta-thalassemia and how they differ in their symptoms and outlook.

Feeling tired and weak all the time and having pale or yellowish skin may be connected to your genes. Alpha thalassemia is an inherited blood disorder in which specific gene mutations that get ...

Alpha-globin genes People have four alpha-globin genes located on chromosome 16. More than 130 possible changes to these genes are associated with alpha-thalassemia.

Alpha-globin and beta-globin protein chains make up hemoglobin. Changes in the alpha- or beta-globin genes that provide instructions for these proteins can lead to thalassemia.

These genes control your body's production of the two proteins that make up hemoglobin, called alpha globin and beta globin. Six genes, three from each parent, are responsible for these two proteins.

Adult hemoglobin, expressed primarily after birth, contains four protein subunits - two beta-globin and two alpha-globin. Mutations in the beta-globin gene cause sickle cell disease and beta ...

The different types of thalassemia develop due to genetic mutations or deletions (where genetic code is missing) in the genes that support alpha and beta globin production.

A Swiss team led by Mandy Boontanrart, PhD, has devised a clever permutation on the gene switching strategy currently progressing in the clinic to compensate for the faulty beta globin gene in the ...

The diagnosis of beta thalassemia major in the propositus and his sister was confirmed by measurement of the incorporation of radioactive amino acid into alpha-globin and beta-globin chains by ...

Mutations in the beta-globin gene cause sickle cell disease and beta-thalassemia. But humans have another hemoglobin subunit gene (gamma-globin), which is expressed during fetal development instead of ...

But humans have another hemoglobin subunit gene (gamma-globin), which is expressed during fetal development instead of beta-globin. Gamma-globin combines with alpha-globin to form fetal hemoglobin.