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At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...
Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells ...
New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations.
The rural region is changing fast as electricians from around the country plug the tech industry’s new, giant data centers into its ample power supply.
Understanding the ways our immune response changes as we age holds the key to designing better vaccines and boosting protection for people most at risk.
A diverse immune response hinges on naive B cells mingling with high affinity ones in the late-stage germinal center. Whether that helps or hinders, however, depends on the virus.
Germinal centers form in the body’s lymphatic tissues shortly after vaccination or infection. Once inside a germinal center, B cells undergo rapid mutations and, through a process of natural ...
While most germinal centers shut down after a few weeks, some stay in business for more than six months. A new study helps explain why.
If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons ...
Ed Baierlein, who founded Germinal Stage Denver in 1973 and oversaw pretty much every decision at the theater, from play selection to casting, outreach to finances and staging to site selection ...
Germinal centers, which form as the result of natural infection or vaccination, are boot camps for immune cells, a place where inexperienced cells are trained to better recognize the enemy and weapons ...
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