Monitoring tumor markers may be an effective relapse-detection strategy for certain children with nongerminomatous malignant germ cell tumors, according to a study published in Journal of Clinical ...

Stem cell markers, OCT3/4, and more recently SOX2 and growth differentiation factor 3 (GDF3), have been reported to be expressed variably in germ cell tumors. We investigated the ...

Serum tumor markers play a more critical role in testicular germ cell tumor management than in any other solid organ malignancy. Here, Barlow and colleagues discuss how the serum levels of AFP ...

After central review, 47 of 48 relapses (98%) were detected by tumor marker elevation. Of the 47 patients, 16 (33.3%) had abnormal tumor markers with normal/unknown imaging, 31 patients (64.6%) had ...

Serum tumour markers in testicular germ cell tumours: Frequencies of elevated levels and extents of marker elevation are significantly associated with clinical parameters and with response to ...

Tumor markers can be used to detect relapse with a high degree of sensitivity in patients with central nervous system nongerminomatous germ cell tumors (CNS-NGGCTs), according to a pooled analysis ...

Pre-orchiectomy serum tumor markers as a predictor of recurrence in stage I germ cell tumors. Rohit R Badia , Rashed Ghandour , Jeffrey Howard , Joseph G Cheaib , Ragheed Saoud , Scott E. Eggener , ...

Doctors can look for these markers to help diagnose ovarian germ cell tumors. CT, or computed tomography scan . This powerful X-ray makes detailed pictures of your ovaries and other organs.

Germ cell tumors: Begin in a person’s germ cells, which produce eggs. Less than 2% of ovarian cancer tumors are germ cell tumors. Scientists also discuss two ovarian cancer subtypes: type 1 and ...

Identification of 22 susceptibility loci associated with testicular germ cell tumors. Nature Communications , 2021; 12 (1) DOI: 10.1038/s41467-021-24334-y Cite This Page : ...

Germ cell cancer can develop in children and adults. Researchers don’t know exactly what causes germ cell cancers to form, but they have identified some risk factors. Germ cell tumors are ...

There are two main types of germ cell tumors in testicular cancer — seminomas and non-seminomas. Non-seminomas develop from germ cells, which are more mature and specialized than they are typically.