Immunohistochemical staining was performed on mouse spleen, brain and spinal ... CD11b was used as microglia/macrophage surface marker; GFAP as an intracellular astrocytic marker; A2B5 as an ...

This study provides a potentially useful investigation into the positive role of BDNF/TrkB signaling in implanted dental pulp stem cells to enhance dentin regeneration in the context of dental caries.

Intraperitoneal injection of LPS (250 µg/kg every alternative day for a total of seven doses over 14 days) triggered glial cell activation, neuroinflammation, oxidative stress, and neurodegeneration ...

In a study supported by the National Institutes of Health (NIH), researchers revealed the structural underpinnings of memory formation across a broad network of neurons in the mouse brain.

An optic fiber would light up if the brain released dopamine and acetylcholine, a neurotransmitter known to regulate dopamine. The researchers found that mouse brains started to release ...

A new AI tool builds sophisticated map of mouse brains. It is a detailed view of the brain like never seen before. In a significant technological leap, University of Florida researchers have ...

New structural markers of memory storage uncovered by Scripps Research may pave the way for new treatments for memory loss.

Brain cells, or oligodendrocytes (green), in the hippocampus are marked with the GFP genetic marker in the mouse brain. These cells often deteriorate during aging. Image credit: Gadek et al., Science ...

They then measured the concentrations of five molecular markers that previous research suggested might hold promise for diagnosing brain injuries: GFAP, neurofilament light chain, amyloid-beta 40 ...

the integrity of brain synapses or on brain markers of Alzheimer’s. The results, said Madeline Wood Alexander, the study’s lead author and a doctoral student at Sunnybrook Research Institute ...