Chris Vasile breaks down the Week 12 slate and offers his best NFL Picks against the spread, including Steelers vs. Browns.

Coming off their first loss of the season, Virginia Tech returns home to Blacksburg, Va., to play Jacksonville Wednesday night in the first meeting between the two schools since 1986.

The Detroit Lions were on the verge of their first Super Bowl appearance, but couldn't finish off the San Francisco 49ers in last season's NFC championship game.