Despite advancements in melanoma therapy, the prognosis remains unfavorable for many patients. The proteasome inhibitor MG132 has shown therapeutic potential through pathway regulation, yet its ...

The aim is to work out how these components fit into signal transduction pathways ... apoptosis, necroptosis and pyroptosis. Keywords: hematopoietic stem cell, skeletal stem cell, melanoma, metastasis ...

HSP70 exerts its anti-apoptotic effects by regulating key effector molecules in apoptotic signaling pathways. Figure 2. Key effector molecules regulated by HSP70 in intrinsic and extrinsic apoptosis ...

Transcriptomic analyses of the UV-treated rats identified 2,332 lncRNAs and 5,906 mRNAs that were differentially expressed, revealing significant involvement in pathways ... For apoptosis, we examined ...

Apoptosis, the dominant form of programmed cell death, refers to the shedding of the leaves from trees in Greek. The distinct morphological changes of cells undergoing apoptosis are sequentially ...