Apoptosis, the dominant form of programmed cell death, refers to the shedding of the leaves from trees in Greek. The distinct morphological changes of cells undergoing apoptosis are sequentially ...

National Cancer Center Research Institute, Tokyo, Japan.

HSP70 exerts its anti-apoptotic effects by regulating key effector molecules in apoptotic signaling pathways. Figure 2. Key effector molecules regulated by HSP70 in intrinsic and extrinsic apoptosis ...

Transcriptomic analyses of the UV-treated rats identified 2,332 lncRNAs and 5,906 mRNAs that were differentially expressed, revealing significant involvement in pathways ... For apoptosis, we examined ...

Despite advancements in melanoma therapy, the prognosis remains unfavorable for many patients. The proteasome inhibitor MG132 has shown therapeutic potential through pathway regulation, yet its ...

When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. Bowser didn't confirm or deny that a new mainline Mario game is in development for the new ...

Metagenomics overcomes the limitations of culture-dependent techniques and is a powerful tool to identify novel resistance genes and to describe the presence or absence of genes or genetic ...

Department of Neurosurgery, Neurological Institute, Taichung Veterans General Hospital, Taichung 407219, Taiwan R.O.C. Department of Physical Therapy, Hung Kuang ...

Abstract: We previously observed that p53-mutated human epithelial tumor A431 cells underwent apoptosis after ultraviolet C (UVC) irradiation through the caspases-8 and -3 pathway. Fas/FasL is known ...

Here, we produce a DNA nanostructure decorated with controlled numbers of engineered single-chain TNF-related apoptosis-inducing ligand (sc-TRAIL ... of the geometric parameters influencing apoptotic ...

This important study shows that nutrient stress emanating from the microenvironment induces metabolic vulnerabilities in pancreatic ductal adenocarcinoma (PDAC). Using a combination of cell-based and ...