CCL3 inhibited erythroid differentiation of hematopoietic stem cells, common myeloid progenitors and especially megakaryocytic-erythroid progenitors. Administration of the CCR1 antagonist ...

Erythropoietin is a naturally occurring glycoprotein hormone, also known as a growth factor, produced in the kidneys that ...

Thyroid hormones stimulate the proliferation of erythroid progenitor cells either directly or by increasing the production of erythropoietin. Second, bleeding may have occurred, further reducing HCT ...

We examine the role of glucocorticoids (GCs) in modulating this process, highlighting how they influence erythroid progenitor proliferation and differentiation through various mechanisms, including ...

Acanthocyte Erythrocyte identified by numerous spiny cytoplasmic projections; similar to a Burr cell Acanthocytosis, condition in which the majority of erythrocytes are acanthocytes. Anemia ...

Tissue-resident stem and progenitor cells are present in many adult organs, where they are important for organ homeostasis and repair in response to injury. However, the signals that activate these ...

Low O2 concentrations enhance the positive effect of IL-17 on the maintenance of erythroid progenitors during co-culture of CD34+ and mesenchymal stem cells.

Progenitor self-renewal and differentiation is often regulated by spatially restricted cues within a tissue microenvironment. Here, we examine how progenitor cell migration impacts regionally induced ...