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Nature Immunology - Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity. Skip to main content.
By inhibiting these receptors, dendritic cells' anti-tumour responses become more effective. "This works a bit like check-point inhibition, which targets T cells, but here the target is the ...
Nature Biotechnology - Dendritic cells, engineered to secrete a T-cell receptor mimic peptide, induce antigen-specific immunosuppression in vivo Skip to main content Thank you for visiting nature.com.
Dendritic cells are a type of antigen-presenting cell ... and even apoptotic body receptors, are present on the DC cell surface and recognize and bind to their target antigens. ...
At the same time, the cell-surface receptors that act as co-receptors in T-cell activation are upregulated by dendritic cells. Furthermore, the CCR7 receptor is also upregulated.
Scientists have discovered why dendritic cell vaccines do not attack ... "We don't know the specific chain of events that Toll-like receptors activate inside dendritic cells to temporarily silence ...
Dendritic cells use phagocytosis to break up molecules from pathogens to present on their cell surface to warn other lymphocytes of an invasion. In a recent study published in Immunity, scientists ...
They carry a receptor on their surface that recognizes small protein fragments – antigens – presented to them by specialized immune cells, including the highly efficient dendritic cells.
Toll-like Receptors & Dendritic Cells in SLE. Toll-like receptors (TLRs) are pathogen recognition systems that identify highly conserved molecular patterns that help distinguish self from non self.
Blastic plasmacytoid dendritic-cell neoplasm (BPDCN) is an aggressive hematologic cancer that is caused by transformed plasmacytoid dendritic cells that overexpress interleukin-3 receptor subunit a ...
Effect of dendritic cells (DC) transduced with chimeric antigen receptor (CAR) on CAR T-cell cytotoxicity. Hyung Chan Suh , Katherine Pohl , Anna Patricia L. Javier , Dennis J. Slamon , John P Chute ...
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