Older, generic medications, including ones for cyclosporine, nicotinamide, and dapsone, can effectively treat patients with various dermatological conditions while helping to reduce insurance and cost ...

METHODS: The CYP enzymes responsible for quetiapine metabolite formation were assessed using recombinant expressed CYPs and CYP-selective inhibitors ... CONCLUSIONS: Cytochrome P450 3A4 is ...

concomitant therapy with a strong cytochrome P-450 3A inhibitor or inducer, clinically important thrombocytopenia or anemia, and conditions felt to put that patient at risk or influence the study ...

School of Medicine and Pharmacy, Key Laboratory of Marine Drugs Ministry of Education, Sanya Oceanographic Institute, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Ocean ...

The recently identified Proton-Activated Chloride (PAC) channel is ubiquitously expressed and has important roles in intracellular organelles and its function in the plasma membrane is associated with ...

Cytochrome P450 (CYP) enzymes are a large class of heme-thiolate protein ... clearance of more than 50% of commonly used clinical drugs, including tyrosine kinase inhibitors, dihydropyridine calcium ...

Dutasteride and tamsulosin are one of the first-line combination therapies for the management of benign prostatic hyperplasia (BPH). Combination therapy is frequent in BPH patients, due to ...