Clear cell renal cell carcinoma (ccRCC) is predominantly treated with anti-angiogenic therapies (AATs), such as sunitinib and axitinib. While these therapies initially improve outcomes, resistance ...
Osaka, Japan – The long-term stasis of blood in the liver, known as chronic liver congestion, can lead to a range of diseases – some of which are fatal. However, identifying how liver congestion ...
Impact of Circulating Tumor DNA and Copy-Number Alterations on Clinical Outcome in Relapsed/Refractory Germ Cell Tumors Treated With Salvage High-Dose Chemotherapy ASCO Guidelines provide ...
Pulmonary fibrosis, an interstitial lung disease, is characterized by progressive thickening and scarring of the lung tissue associated with shortness of breath, decreased vital capacity, and ...
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, primarily due to its dense, desmoplastic and immunosuppressive tumor microenvironment (TME) that hinders the efficacy of ...
Hepatocellular Carcinoma (HCC), a highly prevalent malignancy, poses a significant global health challenge. Its pathogenesis is intricate and multifactorial, involving a complex interplay of ...
The results of the global phase 3 LAPIS trial suggest that the addition of pamrevlumab to standard chemotherapy fails to improve survival outcomes in patients with locally advanced pancreatic cancer ...
A first-in-human phase I trial with antibody drug conjugate ADCT-701 in neuroendocrine tumors and carcinomas. LAPIS: Randomized phase 3 trial of chemotherapy (CTX) with and without pamrevlumab (PAM) ...