CRISPR-Cas tools allow researchers to modify individual building blocks of genetic material in a precise and targeted manner. Gene therapies based on such gene editing are already being used to ...

CRISPR-Cas tools allow researchers to modify individual building blocks of genetic material in a precise and targeted manner. Gene therapies based on such gene editing are already being used to ...

CRISPR-Cas system comprises the adaptive immune system in prokaryotes that disarms invading viruses by cleaving their DNA. Owing to its unique capability of targeting and altering DNA sequences, ...

Genome editing technologies like CRISPR-Cas9 have transformed biology, medicine, and agriculture, but concerns remain about ...

Four Cas protein families, designated Cas1 to Cas4, are strictly associated with CRISPR elements and always occur near a repeat cluster. Computational biologists from the Institute for Genomic ...

CRISPR-Cas variants recognize the target sequences of pathogenic DNA and RNA, collaterally cleaving the ssDNA or ssRNA linked to the fluorophore-quencher or FAM-biotin reporter.

CRISPR-Cas, a defense mechanism that provides bacteria with resistance to their viruses (bacteriophages), destroys DNA from previously encountered adversaries by 'comparing' it to spacers, short ...

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them ...

But CRISPR-Cas now appears to go even further than cutting DNA. “When we discovered CRISPR-Cas, we observed that it cuts viral DNA in precise locations,” explains Brouns.