Frontiers18d
Identification of plant resistance inducers and evaluation of genotype receptivity for carrot protection against Alternaria leaf blight
The results identified plant resistance inducers (PRIs) among biopesticide products capable of protecting carrots against Alternaria leaf blight. By applying a PRI to a range of carrot varieties ...
C&EN20d
Discovery of Potent and Selective MNK Kinase Inhibitors for the Treatment of Leukemia
Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois 60611, United States Division of Hematology and Oncology, Department of Medicine, Feinberg School of Medicine, ...
Frontiers27d
High-performance PBPK model for predicting CYP3A4 induction-mediated drug interactions: a refined and validated approach
Introduction: The cytochrome P450 enzyme 3A4 (CYP3A4) mediates numerous drug-drug interactions (DDIs) by inducing the metabolism of co-administered drugs, which can result in reduced therapeutic ...
C&EN28d
Leveraging Immunogenic Cell Death to Enhance the Immune Response against Malignant Pleural Mesothelioma Tumors
Drug Discovery Lab, Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR 999077, People’s Republic of China Department of Chemistry, National University of ...