This is achieved by infecting a pool of Cas9- expressing cells with ... sequencing datasets that emerge from each single-cell CRISPR screen. “These days, we routinely create close to 10 billion ...

Although gene editing had the potential to improve cell engineering, it would be several years before CAR T cells and CRISPR crossed paths. Finding the path From the beginning, CAR T cells showed ...

A team of researchers at Karolinska Institutet has developed a novel tool for genetic research. The study, published in ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However ...

CRISPR and Vertex's two phase 1/2 studies in thalassaemia and SCD – called CLIMB-111 and CLIMB-211, respectively – have now recruited 19 patients. They are due to enrol 45 apiece, and are ...

Some with severe sickle cell disease in England will now be able to access landmark CRISPR gene editing therapy, according to ...