Chromatin immunoprecipitation (ChIP)-seq confirmed H2AZ1's direct binding to PTN enhancers-regions that regulate the expression of this neurogenic and reparative growth factor, and luciferase ...

In the future, targeted knockout of super‐enhancer regions using CRISPR‐Cas9 (clustered regularly interspaced short palindromic repeats‐associated protein 9) technology could regulate PANoptosis in ...

GA, UNITED STATES, June 17, 2025 / EINPresswire.com / -- In a new discovery that may reshape anti-aging strategies, researchers have identified the histone variant H2A.Z variant histone 1 (H2AZ1) as a ...

To quantity SNHG de-regulation at higher resolution, we created a custom annotation in which we divided each SNHG into exonic regions, the snoRNA-encoding region, regions in the snoRNA-containing ...

The use of chemical permeation enhancers (PEs) to improve the permeation of peptides across gastric and intestinal epithelia has proven an effective strategy in the development of oral dosage forms of ...

Reviewer #3 (Public review): Summary: The tissue regeneration enhancer elements (TREEs) identified in zebrafish have been shown to drive injury-activated temporal-spatial gene expression in mice and ...

The switch from fetal γ-globin to adult β-globin is controlled by BCL11A. Genetic manipulation of BCL11A improves disease outcomes by turning γ-globin expression back on to compensate for ...