Cancer Research UK-funded scientists based at the University of Cambridge have identified a new target for the treatment of lung squamous cell carcinoma. Subscribe Advertise ...

Essentially, cereblon and its target proteins can change shape to form a complex with the cereblon, the target, and the ...

The new drug target is the BCL11A gene, which researchers zeroed in on by studying 3,000 breast cancers and the genes that affect stem cells and developing tissue. Dr. Pentao Liu ...

Triple-negative breast cancer (TNBC) refers to any breast cancer that does not express the oestrogen receptor (ER), progesterone receptor (PR) and HER2 receptor; this disease subtype accounts for ...

The first wave of targets has been classically druggable, where degradation-based therapies offer an alternative, and perhaps superior, mechanism of action to existing approved drugs. However, we are ...