Wojciech Jurczak, MD, PhD, discusses advancements in B-cell lymphoma therapy, focusing on immunotherapy, molecular-targeted agents, and more.

Our blood consists of many cell types that develop through different stages from a precursor type -- the blood stem cell. An international research team has now investigated the developmental pathways ...

Germinal centers are machines of rapid evolution. Germinal centers are tiny clusters in the lymph nodes that refine antibodies through proliferation and mutation to create high-affinity B cells that ...

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and ...

New study demonstrates how high-affinity B cells "bank" their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design.

We spoke with Mark Boothby, Professor of Immunology at Vanderbilt University, about his experience publishing with eLife.

Switching to islatravir and doravirine was just as effective as bictegravir/emtricitabine/tenofovir alafenamide fumarate (BIC ...

They also show that models learned from nonsynonymous mutations and from out-of-frame sequences are different, prompting new questions about germinal center function. Strengths of the study include an ...