Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...
is downregulated in activated microglia after traumatic brain injury in mice. This decrease in Tmem119 immunoreactivity was observed in both amoeboid microglia, which are typically observed in the ...
We aim to provide basic knowledge on how the brain's innate immune cells (microglia) govern neurological disorders. Microglia are the primary resident immune cells of the brain and as such play a ...
Although few studies have investigated the impact of BPA on microglia morphology, prior literature suggests that BPA increases amoeboid microglia numbers in the murine neocortex of weanlings exposed ...
Following CSF1Ri, these amoeboid cells migrate radially and tangentially in a dynamic wave filling the brain in a distinct pattern, to replace the microglial-depleted brain. These repopulating cells ...
Why is it important to know the proportion of microglia in astroglial cultures and to keep this proportion as low as possible? First, because astrocytes and microglia are very different types of ...
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