The latest HPRA inspection in February 2025 was highly successful-both QC licences were renewed, and viral vector manufacturing was added to the MIA (IMP) licence. This means the Shannon site can ...

Bio-Rad Laboratories, Inc has introduced Vericheck ddPCR™ Empty-Full Capsid Kits for adeno-associated virus (AAV) serotypes 2 ...

Forbes Porter, from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and coauthors assessed the prevalence of anti-AAV9 and anti-AAV2 neutralizing antibodies ...

Forbes Porter, from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and coauthors assessed the prevalence of anti-AAV9 and anti-AAV2 neutralizing antibodies ...

Gene therapy involves the introduction of new genes into cells, to restore or add gene expression, for the purpose of treating disease. Most commonly a mutated gene is replaced with DNA encoding a ...

The gene augmentation product was a recombinant AAV8 vector expected to express AIPL1 in both rods and cones. The better-seeing eye of each of the four children (age range 1–3 years; two males and two ...

Approximately 0.05–0.1 µl of AAV2-hSyn-tdTomato was injected directly into the suprapyramidal ... biotinylated goat anti-rabbit Immunoglobin G secondary antibody (1:200; Vector Laboratories, ...

Mechanistic studies of axon growth during development are beneficial to the search for neuron-intrinsic regulators of axon regeneration. Here, we discovered that, in the developing neuron from rat, ...

Three of the tumor-bearing mice received the AAV2 vector and four received the AAV-PTP vector. For IV injection, mice were anesthetized with 1–1.2% isoflurane in oxygen. Viral solutions containing 1 × ...