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In addition, discontinuation of a concomitantly used cytochrome P450 3A4 inducer may result in an increase in hydrocodone plasma concentration.
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In addition, discontinuation of a concomitantly used cytochrome P450 3A4 inducer may result in an increase in sufentanil plasma concentration.
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Cytochrome P450 3A4 (CYP3A4) and CYP2C19 were involved in the metabolism of triptolide in human liver microsomes and that CYP3A4 was the primary isoform responsible for its hydroxylation 10.
Dose adjustments of antidiabetic agents may be required. CYP 3A4 inducers and inhibitors: May respectively increase or decrease clearance of corticosteroids necessitating dose adjustment.
An evaluation of the drug interaction potential of netupitant with substrates, inhibitor and inducer of CYP3A4. Authors: Klaus Peter Kammerer, Giorgia Rossi, Selma Calcagnile, and Wolfgang Timmer ...
The increasing use of dietary supplements by patients with cancer and other chronic diseases requires the systematized review of potential interactions between prescription drugs and nutrients from ...