A prototype nanoparticle biosensor based on localized surface plasmon resonance (LSPR) spectroscopy was developed to detect drug binding to human membrane-bound cytochrome P450 3A4 (CYP3A4). CYP3A4 is ...

Inducers frequently increase the activity of CYP450 enzymes involved in alternative metabolic pathways, although some may induce their own metabolism. Unlike enzyme inhibition, the peak effect of an ...

Talk with your doctor or registered dietitian before starting any new supplements to ensure they make sense for your health needs and are the right supplements to help you reach your workout goals.

Covalent binding of reactive metabolites to cytochrome P450s (P450s) often causes their mechanism-based inactivation (MBI), resulting in drug–drug interactions or toxicity. The detection and ...

A recent Harvard study reveals that vitamin D supplements may slow biological aging by protecting telomeres, offering potential anti-aging benefits.

Vitamin D supplements are popular for bone health and immunity. When is the best time to take vitamin D? Here's how to take it properly, according to experts.

Many medical and nutritional experts strongly support dietary supplements. But it's not all good news. Here's how to weigh the pros and cons.

iHerb has recalled 60,000 bottles and blister packs of California Gold Nutrition iron-containing supplements due to lack of child-resistant packaging, posing a risk of fatal poisoning to children.

The supplements included in this list were chosen because some research has found a potential benefit for joint health, though whether you decide to take one will depend on the medications you're ...

Dolutegravir demonstrates little to no inhibition or induction of transporters P-glycoprotein, breast cancer resistance protein, multidrug resistance protein 2 or 4, organic anion transporting ...