Introduction Patients referred to a Tertiary Airways and Severe Asthma Service for refractory breathlessness may be diagnosed with Breathing Pattern Disorder (BPD) or Inducible Laryngeal Obstruction ...
Introduction Lung cancer outcomes in England are inferior to comparable countries. Patient or disease characteristics, healthcare-seeking behaviour, diagnostic pathways, and oncology service provision ...
BACKGROUND Cystic fibrosis is characterised by oxidative stress in the airways. Isoprostanes are prostaglandin isomers formed by free radical catalysed peroxidation of arachidonic acid. 8-Isoprostane ...
Objective NEWS2 (RCP 2017) 1 recommends use of ‘SpO2 Scale 2’ in patients with hypercapnic respiratory failure (usually due to COPD) to aim target saturations of 88–92%. We aimed to identify if COPD ...
3 The University of Manchester, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UK 4 University Hospital of South Manchester, ...
BACKGROUND Obesity and increased neck circumference are risk factors for the obstructive sleep apnoea/hypopnoea syndrome (SAHS). SAHS is more common in men than in women, despite the fact that women ...
Division of Pulmonary Disease and Laboratory of Cytoimmunopathology of Heart and Lung, Salvatore Maugeri Foundation, IRCCS, Veruno, Italy Background: Increased numbers of activated neutrophils have ...
A review of 839 necropsies revealed 415 cases of malignant neoplasm, 63 of which were found to have evidence of metastatic spread to the sternum. Nineteen of these metastases resulted in pathological ...
Background: Effective strategies for managing patients with solitary pulmonary nodules (SPN) depend critically on the pre-test probability of malignancy. Objective: To validate two previously ...
Correspondence to Professor Heather J Zar, Department of Paediatrics and Child Health, 5th Floor, ICH Building, Red Cross War Memorial Children's Hospital, Cape Town 7700, South Africa; heather.zar{at ...
Correspondence to Dr Charlotte Summers, Division of Anaesthesia, Department of Medicine, Box 93, Level 4, Addenbrooke's Hospital, CUHNHSFT, Hills Road, Cambridge CB2 OQQ, UK; ...
Richard Morton was one of the outstanding physicians of the seventeenth century. After graduating BA at Oxford he elected to enter the Church, becoming ultimately Vicar of Kinver in Staffordshire. On ...
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