Aging of the brain is characterized by deleterious processes at various levels including cellular/molecular and ...

Lu]Lu-PSMA-617 radiopharmaceutical therapy has been approved for the treatment of men with metastatic castration-resistant ...

Giri et al. present a case report involving a patient with metachronous low-volume metastatic hormone-sensitive prostate cancer (mHSPC) who declined standard treatments such as androgen deprivation ...

Journal of Nuclear Medicine September 2025, jnumed.125.270267; DOI: https://doi.org/10.2967/jnumed.125.270267 ...

Journal of Nuclear Medicine September 2025, jnumed.124.268809; DOI: https://doi.org/10.2967/jnumed.124.268809 ...

Journal of Nuclear Medicine September 2025, jnumed.125.269688; DOI: https://doi.org/10.2967/jnumed.125.269688 ...

Targeting tumors with antibody-based therapeutics is a complex task presenting multiple kinetic barriers. Antibody internalization and clearance inhibit uptake both in solid tumors, limited by tumor ...

In most types of peptide receptor radionuclide therapy, the maximum activity dose that can be administered is limited by high and persistent renal retention of the radiolabeled peptides, which is, at ...

Molecular imaging is a rapidly emerging research tool and clinical discipline aimed at noninvasive, quantitative visualization of in vivo molecular processes occurring at cellular and subcellular ...

Animal models have been instrumental in elucidating key biochemical and physiologic processes of cancer onset and propagation in a living organism. Most importantly, they have served as a surrogate ...

Because metabolic changes may precede changes in lesion morphology, there is growing interest in applying 18 F-FDG PET as an adjunct to anatomic imaging for the evaluation of chemotherapeutic response ...

Quantitative 18F-FDG PET is increasingly being recognized as an important tool for diagnosis, determination of prognosis, and response monitoring in oncology. However, PET quantification with, for ...