Myotonic dystrophy type 1 (DM1) is the most common adult-onset form of muscular dystrophy and a condition that severely ...

Researchers at Baylor College of Medicine and their collaborators focused on Myotonic Dystrophy 1 heart problems testing a novel approach to restore normal function.

Our cells harbor a DNA detector termed cGAS to inform the immune system of viral and bacterial infections, cell death, as ...

Researchers at the Kennedy Institute have developed a new computational framework that allows simultaneous analysis of gene expression and mechanical forces within cells and tissues, uncovering ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

A research team has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses. Their findings could open new pathways for ...

A novel mouse model offers definitive evidence that a single inhibitory receptor family governs the critical natural killer cell functions of licensing and missing-self.

A gene regulatory network is a set of genes, or parts of genes, that interact with each other to control a specific cell function. Gene regulatory networks are important in development ...

A118G (43AA, 19AG, 18GG) 80 Taiwan females following abdominal hysterectomy GG had significantly higher postoperative day 1 morphine requirements [104] A118G Caucasians: 66 = AA, 29AG; Africans: 1 ...

Modifications can be generated by methods such as gene targeting, nuclear transplantation, transfection of synthetic chromosomes or viral insertion. Selective breeding is not considered a form of ...