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In this work, we carried out neurochemical and behavioral analysis of zebrafish (Danio rerio) treated with rotenone, an agent used to chemically induce a syndrome resembling Parkinson’s disease (PD).
The effects of CTAB-AuNRs on the development of zebrafish embryos exhibited an “all-or-nothing” response as only embryos exposed to the highest concentration showed developmental anomalies, including ...
NUZ-001 and its active metabolite NUZ-001 Sulfone demonstrated significant neuroprotective effects in a zebrafish model of Huntington's disease Treatment prevented hallmark developmental and ...
Microscopic ovary features of Zebrafish were analyzed. Samples were fixed in Bouin s solution, mounted in parafin and cut into 6-7 µm-thick slices which were stained with Hematoxylin and Eosin (HE), ...
The larval zebrafish is also quite small (∼5 mm in length), making it amenable to large-scale robotic screening, and several drugs from zebrafish screens are currently in clinical development [40–42].
Zebrafish model for an ultra-rare genetic disease reveals two promising drug candidates by Jeff Hansen, University of Alabama at Birmingham edited by Stephanie Baum , reviewed by Robert Egan ...
In a study published in EMBO Molecular Medicine, Alexander and Dowling now show that their mutant zebrafish have weakened muscles and other symptoms that mirror human XMEA disease. With this simple ...
A Coram prankster who recorded himself dumping eggs and black beans over his head at local eateries to boost his TikTok following now faces serious criminal charges — and he’s using the moment to ask ...
We generated 27 zebrafish mutants with presumptive protein-truncating mutations or specific missense variants corresponding to autism-risk alleles in 17 human genes. We observed baseline and ...