Hosted on MSN9d
People with this rare genetic condition can't repair damage to their DNA
LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...
Medscape3d
CAR T-Cell Therapy Safe in Those With Autoimmune Disease
CAR T-cell therapy for cancer leads to similar safety and cancer outcomes in patients with and without preexisting autoimmune ...
Nature10d
20 years of gene therapy for SCID
Severe combined immunodeficiency conditions are devastating ... Further extension to other T cell immunodeficiencies or more complex immunodeficiencies (Wiskott-Aldrich syndrome, for example ...
Health and Me on MSN4d
What Is The Difference Between HIV And AIDS?
The first known case of HIV-1 infection in human was detected in 1959, from a blood sample of a man in Kinshasa, Democratic ...
technologynetworks11d
Study Finds No Evidence CAR T-Cell Therapy Causes Secondary Cancers
A study of 783 patients treated with CAR T cell therapy found no evidence that the therapy itself caused secondary cancers.
Saint Louis University11mon
Division of Allergy and Immunology
The division works with the Bone Marrow Transplantation Division in transplantation of severe T-cells immunodeficiency and other Primary Immunodeficiency Disorders. The A&I Division is a referral ...
The Scientist11mon
Stem Cell Editing Repairs Severe Immunodeficiency
While other research groups had successfully added RAG1 to patient HSC, they were unable to properly regulate expression of the gene, and therefore couldn’t ensure that the stem cells were safe or ...
Medical Xpress on MSN12d
New study confirms CAR T cell therapy does not cause secondary cancers
such as in a French trial of gene therapy to correct X-linked severe combined immunodeficiency, where 25 percent of study participants developed leukemia from the therapy. Reaffirming the safety ...